Healthcare
New Study Shows Mood, Mental Health Improved by Microdosing Psilocybin
A study funded by Quantified Citizen, co-authored by Paul Stamets, proves that psilocybin treatment can help boost mood and mental health.
A study published in Scientific Reports on June 30 has presented evidence that psilocybin mushrooms have a noticeable effect on the mood and mental health of participants.
The study, called “Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls,” analyzed 1,133 subjects between November 2019 to May 2021. Baseline assessment was conducted at the beginning of the study, and then again between 22-35 days later.
Researchers analyzed the results of psilocybin microdosing combined with either lion’s mane mushrooms (Hericium erinaceus, or abbreviated as HE) or niacin (vitamin-B3) to identify “small- to medium-sized improvements in mood and mental health that were generally consistent across gender, age and presence of mental health concerns … improvements in psychomotor performance that were specific to older adults.” The study refers to these combinations as “stacking.”
The study abstract notes that combining psilocybin with HE or B3 “did not impact changes in mood and mental health,” however, older participants did experience psychomotor improvements through either just psilocybin, or psilocybin and HE.
The research was written by numerous authors including Paul Stamets, as well as Joseph M. Rootman of University of British Columbia’s Department of Psychology. According to an interview with Forbes, Rootman is certain that the work being conducted now will help lead to more revelations in the future. “This study is an extension of our earlier manuscript published in the same journal, and we have further publications in preparation that are based on this same study,” said Rootman. “Our team has also been working hard to develop the next version of the study which will be used to generate findings related to psychedelic microdosing for years to come.”
Rootman also clarified that the study did not require just one type of mushroom variety. Rather, researchers simply observed the patient’s recorded experiences, which ranged between low, medium, or high microdosed amounts of mushrooms (0.1 grams, 0.1-0.3 grams, or more than 0.3 grams, respectively). “We found that about 10% of our microdosing sample in this study reported high dosages, 72.6% reported medium dosages, and 16.8% reported low dosages,” Rootman added.
The study description shares the authors’ collective belief that this is one of the first studies of its kind, but requires more research in order to build up a foundation to showcase how psilocybin can benefit human participants. “Further research with control groups and large samples that allow for the examination of potential moderators such as mental health status, age, and gender are required to better appreciate the health consequences of this emerging phenomenon,” the authors concluded. “In the present study, we aim to extend this literature by examining prospective changes associated with microdosing psilocybin as compared to a non-microdosing control group on domains of mental health, mood, and cognitive and psychomotor functioning. To our knowledge, this is the largest prospective study to date of microdosing psilocybin, the first to distinguish between microdosing admixtures (i.e., stacking), and among the few prospective studies to systematically disaggregate analyses according to age and mental health concerns.”
Gradually, more evidence is being collected in studies such as this one. However it is not yet enough to convince those who oppose the use of medical psilocybin. At the end of June, Linn County, Oregon announced the approval of a voter’s initiative to ban psilocybin therapy and treatment centers (even though the rest of the state will embrace the voter-approved psilocybin therapy program that is slated to begin in 2023).
Earlier last month, a South Africa-based study found that psilocybin can help treat women with HIV and depression. Another study from April also discovered that psilocybin has potential as a treatment for depression. In May, activists from Right to Try organization recently protested outside of the Drug Enforcement Administration’s headquarters in Virginia to bring attention to patients who could use psilocybin to improve their quality of life.
Source: https://hightimes.com/study/new-study-shows-mood-mental-health-improved-by-microdosing-psilocybin/
Education News
AIIMS Gorakhpur Reservation Controversy: FIR Alleges Fake OBC Certificate Used Despite ₹80 Lakh Income
A major controversy has emerged at AIIMS Gorakhpur after allegations surfaced that reservation benefits were misused to secure a postgraduate medical seat. A criminal case has been registered against former AIIMS Gorakhpur Executive Director Dr. G.K. Pal and his son, Dr. Oro Prakash Pal, over the alleged use of a forged Other Backward Class (OBC) Non-Creamy Layer certificate for admission to an MD course.
The case has triggered widespread debate within medical and administrative circles, raising serious questions about transparency and oversight in admissions to premier medical institutions.
FIR Filed on Court’s Direction
The First Information Report (FIR) was registered at the AIIMS police station following directions from Chief Judicial Magistrate Tvishi Srivastava. According to the complaint, the alleged offence took place on August 30, 2024, when forged documents were purportedly used to obtain an MD seat under the OBC reservation quota.
Sources indicate that the matter was subsequently brought to the attention of the Union Ministry of Health, prompting internal reviews and administrative action.
Alleged Income Far Above Eligibility Threshold
Central to the allegations is the claim that Dr. G.K. Pal and his wife Parvati Pal have a combined annual income exceeding ₹80 lakh. Under existing reservation rules, families with such income levels are not eligible for OBC Non-Creamy Layer benefits.
Following the emergence of the controversy, Dr. Pal was first removed from his position at AIIMS Gorakhpur and later relieved of responsibilities at AIIMS Patna. He is currently posted at JIPMER Puducherry. With the registration of the FIR, officials suggest that further legal and departmental action may follow, depending on the outcome of the investigation.
Complaint Highlights Systemic Concerns
The complaint was filed by Ashutosh Kumar Mishra, a resident of Divyanagar in the Cantonment area. He alleged that the events related to the case occurred between January and September 2024. The complainant argued that misuse of reservation provisions by individuals in senior positions undermines the integrity of public institutions and erodes trust in the medical education system.
The case has reignited concerns over whether verification mechanisms for reservation certificates are robust enough, particularly in high-stakes admissions.
Impact on Medical Community
The allegations have sent shockwaves through the medical fraternity. Experts believe that if the claims are substantiated, the case could prompt a broader review of admission procedures and lead to stricter scrutiny of category certificates across institutions like AIIMS.
Authorities have stated that all relevant documents will be carefully examined before taking further steps. The outcome of the investigation is expected to have far-reaching implications for accountability and compliance in medical admissions.
Questions Await Answers
As the probe continues, several key issues remain unresolved: whether reservation norms were deliberately violated, how verification processes failed, and whether similar cases may surface in the future. For now, the focus remains on the investigation and its potential consequences.
Business
New Mexico cannabis operator fined, loses license for alleged BioTrack fraud
New Mexico regulators fined a cannabis operator nearly $300,000 and revoked its license after the company allegedly created fake reports in the state’s traceability software.
The New Mexico Cannabis Control Division (CCD) accused marijuana manufacturer and retailer Golden Roots of 11 violations, according to Albuquerque Business First.
Golden Roots operates the The Cannabis Revolution Dispensary.
The majority of the violations are related to the Albuquerque company’s improper use of BioTrack, which has been New Mexico’s track-and-trace vendor since 2015.
The CCD alleges Golden Roots reported marijuana production only two months after it had received its vertically integrated license, according to Albuquerque Business First.
Because cannabis takes longer than two months to be cultivated, the CCD was suspicious of the report.
After inspecting the company’s premises, the CCD alleged Golden Roots reported cultivation, transportation and sales in BioTrack but wasn’t able to provide officers who inspected the site evidence that the operator was cultivating cannabis.
In April, the CCD revoked Golden Roots’ license and issued a $10,000 fine, according to the news outlet.
The company requested a hearing, which the regulator scheduled for Sept. 1.
At the hearing, the CCD testified that the company’s dried-cannabis weights in BioTrack were suspicious because they didn’t seem to accurately reflect how much weight marijuana loses as it dries.
Company employees also poorly accounted for why they were making adjustments in the system of up to 24 pounds of cannabis, making comments such as “bad” or “mistake” in the software, Albuquerque Business First reported.
Golden Roots was fined $298,972.05 – the amount regulators allege the company made selling products that weren’t properly accounted for in BioTrack.
The CCD has been cracking down on cannabis operators accused of selling products procured from out-of-state or not grown legally:
- Regulators alleged in August that Albuquerque dispensary Sawmill Sweet Leaf sold out-of-state products and didn’t have a license for extraction.
- Paradise Exotics Distro lost its license in July after regulators alleged the company sold products made in California.
Golden Roots was the first alleged rulebreaker in New Mexico to be asked to pay a large fine.
Source: https://mjbizdaily.com/new-mexico-cannabis-operator-fined-loses-license-for-alleged-biotrack-fraud/
Business
Alabama to make another attempt Dec. 1 to award medical cannabis licenses
Alabama regulators are targeting Dec. 1 to award the first batch of medical cannabis business licenses after the agency’s first two attempts were scrapped because of scoring errors and litigation.
The first licenses will be awarded to individual cultivators, delivery providers, processors, dispensaries and state testing labs, according to the Alabama Medical Cannabis Commission (AMCC).
Then, on Dec. 12, the AMCC will award licenses for vertically integrated operations, a designation set primarily for multistate operators.
Licenses are expected to be handed out 28 days after they have been awarded, so MMJ production could begin in early January, according to the Alabama Daily News.
That means MMJ products could be available for patients around early March, an AMCC spokesperson told the media outlet.
Regulators initially awarded 21 business licenses in June, only to void them after applicants alleged inconsistencies with how the applications were scored.
Then, in August, the state awarded 24 different licenses – 19 went to June recipients – only to reverse themselves again and scratch those licenses after spurned applicants filed lawsuits.
A state judge dismissed a lawsuit filed by Chicago-based MSO Verano Holdings Corp., but another lawsuit is pending.
Source: https://mjbizdaily.com/alabama-plans-to-award-medical-cannabis-licenses-dec-1/
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