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New Study Shows Mood, Mental Health Improved by Microdosing Psilocybin

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A study funded by Quantified Citizen, co-authored by Paul Stamets, proves that psilocybin treatment can help boost mood and mental health.

A study published in Scientific Reports on June 30 has presented evidence that psilocybin mushrooms have a noticeable effect on the mood and mental health of participants.

The study, called “Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls,” analyzed 1,133 subjects between November 2019 to May 2021. Baseline assessment was conducted at the beginning of the study, and then again between 22-35 days later.

Researchers analyzed the results of psilocybin microdosing combined with either lion’s mane mushrooms (Hericium erinaceus, or abbreviated as HE) or niacin (vitamin-B3) to identify “small- to medium-sized improvements in mood and mental health that were generally consistent across gender, age and presence of mental health concerns … improvements in psychomotor performance that were specific to older adults.” The study refers to these combinations as “stacking.”

The study abstract notes that combining psilocybin with HE or B3 “did not impact changes in mood and mental health,” however, older participants did experience psychomotor improvements through either just psilocybin, or psilocybin and HE.

The research was written by numerous authors including Paul Stamets, as well as Joseph M. Rootman of University of British Columbia’s Department of Psychology. According to an interview with Forbes, Rootman is certain that the work being conducted now will help lead to more revelations in the future. “This study is an extension of our earlier manuscript published in the same journal, and we have further publications in preparation that are based on this same study,” said Rootman. “Our team has also been working hard to develop the next version of the study which will be used to generate findings related to psychedelic microdosing for years to come.”

Rootman also clarified that the study did not require just one type of mushroom variety. Rather, researchers simply observed the patient’s recorded experiences, which ranged between low, medium, or high microdosed amounts of mushrooms (0.1 grams, 0.1-0.3 grams, or more than 0.3 grams, respectively). “We found that about 10% of our microdosing sample in this study reported high dosages, 72.6% reported medium dosages, and 16.8% reported low dosages,” Rootman added.

The study description shares the authors’ collective belief that this is one of the first studies of its kind, but requires more research in order to build up a foundation to showcase how psilocybin can benefit human participants. “Further research with control groups and large samples that allow for the examination of potential moderators such as mental health status, age, and gender are required to better appreciate the health consequences of this emerging phenomenon,” the authors concluded. “In the present study, we aim to extend this literature by examining prospective changes associated with microdosing psilocybin as compared to a non-microdosing control group on domains of mental health, mood, and cognitive and psychomotor functioning. To our knowledge, this is the largest prospective study to date of microdosing psilocybin, the first to distinguish between microdosing admixtures (i.e., stacking), and among the few prospective studies to systematically disaggregate analyses according to age and mental health concerns.”

Gradually, more evidence is being collected in studies such as this one. However it is not yet enough to convince those who oppose the use of medical psilocybin. At the end of June, Linn County, Oregon announced the approval of a voter’s initiative to ban psilocybin therapy and treatment centers (even though the rest of the state will embrace the voter-approved psilocybin therapy program that is slated to begin in 2023).

Earlier last month, a South Africa-based study found that psilocybin can help treat women with HIV and depression. Another study from April also discovered that psilocybin has potential as a treatment for depression. In May, activists from Right to Try organization recently protested outside of the Drug Enforcement Administration’s headquarters in Virginia to bring attention to patients who could use psilocybin to improve their quality of life.

Source: https://hightimes.com/study/new-study-shows-mood-mental-health-improved-by-microdosing-psilocybin/

Cannabis & Policy

Supreme Court Raises Concern Over Steep Medicine Mark-Ups at Corporate Hospitals

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The Supreme Court of India has questioned the sharp difference between the prices at which medicines reach retailers and the maximum retail prices charged to patients, particularly in corporate hospitals.

During a hearing on September 29, a bench of Justices Vikram Nath and Sandeep Mehta examined whether a uniform limit of 16% could be applied to medicine margins. The discussion followed the court’s earlier concern over a cancer medicine with a retailer price of about ₹2,700–₹3,000 but an MRP of ₹27,000.

Court Questions Wide Gap Between Retail Price and MRP

The Supreme Court focused on how such large differences between the Price to Retailer (PTR) and MRP can affect patients who have little choice over where they obtain medicines during hospital treatment.

The bench questioned why different pricing rules should apply to essential and non-essential medicines and asked whether a common 16% margin could be considered across pharmaceutical products. The issue remains under consideration and the court has not imposed such a cap at this stage.

Concerns Over In-House Hospital Pharmacies

The court also examined the purchasing practices of corporate hospitals.

According to the proceedings, patients admitted to some hospitals may be directed to obtain medicines from the facility’s own pharmacy. The bench raised concerns about situations in which hospitals may not accept medicines purchased from outside pharmacies or may decline to provide treatment assurances when patients bring their own drugs.

The issue becomes particularly significant for patients undergoing expensive or long-term treatments, where medicine costs can represent a substantial part of the overall bill.

Impact on Government Health Schemes

The Supreme Court also highlighted the potential effect of high medicine prices on publicly funded healthcare programmes.

Where treatment is reimbursed under government schemes, the court noted that taxpayers ultimately finance the medical expenses. If reimbursement is calculated using substantially inflated MRPs, the difference between procurement costs and the amount reimbursed could increase public expenditure.

The bench also pointed to a consumer-trust problem. If a medicine officially carries an MRP of ₹27,000 but a pharmacy offers it for around ₹3,000, patients may question whether the cheaper medicine is genuine.

Government Seeks Time to Examine the Issue

Solicitor General Tushar Mehta, appearing for the Centre, told the court that the government would need to work out a balanced approach.

The government has been asked to examine the issue with relevant officials before responding further. The court granted additional time for consultations rather than immediately introducing a new pricing rule.

The proceedings are part of a broader case concerning medicine pricing, generic prescriptions and regulation of medical costs. The Supreme Court’s official website lists Justice Vikram Nath and Justice Sandeep Mehta as sitting together in Court No. 2 on September 29, 2026.

Court’s Earlier Warning on Medicine Pricing

The latest hearing follows strong observations made by the Supreme Court earlier in September after it examined the pricing of cancer medicines.

The bench had highlighted an example where a medicine costing roughly ₹2,700 at the retailer level carried an MRP of ₹27,000. The court questioned how such a substantial price difference could be justified when patients are dependent on life-saving medicines.

The court also heard arguments that pharmaceutical manufacturers may not necessarily retain the entire difference between the retailer price and the final amount charged to patients, with significant margins potentially arising at later stages of the supply chain, including retail and hospital sales.

What Happens Next?

The Supreme Court has not yet ordered a nationwide 16% medicine-margin cap. Instead, it has asked the government to consider possible regulatory solutions and return with its response.

The matter is scheduled for further hearing on October 12, when the court is expected to consider the government’s position on medicine pricing and related issues.

Any eventual regulatory change could have implications for patients, hospitals, pharmacies, pharmaceutical companies and government-funded healthcare programmes. For now, the 16% figure remains a proposal raised during the court proceedings rather than an operative rule.

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Economic Fraud

Fugitive Medicare Fraud Suspect Returned to US After Arrest in Türkiye

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U.S. federal authorities have secured the return of a fugitive suspect accused of involvement in a massive Medicare fraud operation, following his arrest in Türkiye. The extradition marks a significant development in a major healthcare fraud investigation that allegedly cost the American healthcare system billions of dollars.

The suspect, Ibrahim Khaldoon Hilmi, is now in federal custody after spending more than a year outside the United States. Prosecutors are expected to move forward with criminal proceedings as investigators continue to examine what authorities describe as a sophisticated fraud network targeting public healthcare funds.

International Manhunt Ends with Arrest in Türkiye

According to federal investigators, Hilmi left the United States in May 2025 while authorities were building their case. Law enforcement agencies later tracked his location to Türkiye, where cooperation between U.S. and Turkish officials led to his detention.

Following the completion of legal and diplomatic procedures, the suspect was transferred to American custody. Officials described the operation as a successful example of international law enforcement collaboration in pursuing suspects accused of large-scale financial crimes.

A specialized FBI team reportedly traveled to Türkiye to coordinate the transfer and ensure the extradition process was completed smoothly.

Alleged Scheme Targeted Medicare Reimbursement System

Investigators allege that Hilmi played a central role in a fraudulent operation that exploited the Medicare reimbursement system through false claims and improper billing practices.

Authorities estimate that the alleged scheme involved financial losses equivalent to approximately ₹31,700 crore, making it one of the most significant healthcare fraud investigations in recent years.

While the allegations have yet to be tested in court, investigators believe the operation relied on complex financial transactions and coordinated activities designed to extract funds from a government healthcare program serving millions of beneficiaries.

Federal Agencies Expand Investigation

The case extends beyond a single suspect. Federal authorities are examining the potential involvement of additional individuals, businesses, and organizations believed to be connected to the alleged fraud network.

Investigators are reviewing banking records, financial transactions, corporate structures, and digital evidence to determine the full scope of the operation and identify any additional participants.

Officials indicated that tracing the movement of funds and uncovering potential links between entities remains a key focus of the ongoing investigation.

Healthcare Fraud Remains a Major Concern

Government agencies continue to treat Medicare fraud as a serious threat because it impacts taxpayer-funded healthcare resources intended for legitimate medical services.

Authorities argue that fraudulent claims can divert critical funding, increase administrative costs, and place additional pressure on public healthcare programs. As healthcare systems become increasingly digitized, fraud schemes have also become more sophisticated and difficult to detect.

Financial crime specialists note that modern healthcare fraud investigations often involve shell companies, layered transactions, and cross-border financial networks that require extensive forensic analysis.

Growing Importance of Global Law Enforcement Cooperation

The successful return of Hilmi highlights the increasing role of international cooperation in combating financial crime. Law enforcement agencies worldwide are relying more heavily on cross-border partnerships to locate and apprehend suspects who attempt to evade prosecution by relocating overseas.

Officials say such collaborations are essential as financial crimes become increasingly global in nature, involving multiple jurisdictions and complex international money flows.

Legal Proceedings Ahead

The U.S. Department of Justice is expected to present evidence against the suspect as court proceedings move forward. Prosecutors will seek to establish the extent of the alleged fraud and determine accountability among those involved.

The outcome of the case could influence future enforcement efforts aimed at protecting public healthcare programs and strengthening safeguards against large-scale financial misconduct.

For federal authorities, the extradition of Ibrahim Khaldoon Hilmi represents a major step in an ongoing campaign to crack down on healthcare fraud and recover public funds allegedly lost through criminal schemes.

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Cyber Crime

Telangana Doctors Lose Nearly ₹30 Crore to Cyber Fraud Since September 2024

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Cybercriminals have defrauded doctors across Telangana of nearly ₹30 crore since September 2024, prompting authorities to strengthen awareness campaigns and cybersecurity education within the healthcare sector.

The alarming figures were revealed during a cyber awareness programme organized by the Telangana Cyber Security Bureau (TGCSB) in Hyderabad. Senior officials warned that healthcare professionals are increasingly becoming targets of sophisticated online scams despite their educational and professional backgrounds.

Healthcare Professionals Under Growing Cyber Threat

Addressing representatives from various medical associations, TGCSB Director Shikha Goel highlighted the rising number of cybercrime incidents involving doctors and healthcare workers. She emphasized that cybercriminals are exploiting digital platforms to target individuals across all professions, including highly qualified medical practitioners.

Officials stressed that vigilance, awareness, and prompt reporting remain the strongest defenses against cyber fraud. The event focused on strengthening cooperation between law enforcement agencies and the medical fraternity to improve preparedness against evolving cyber threats.

More than 70 office-bearers from medical organizations across Telangana attended the session, including presidents, secretaries, treasurers, and senior representatives.

Investment Scams Responsible for Major Financial Losses

According to TGCSB data, at least 735 doctors have reported cybercrime-related incidents since September 2024, with total losses reaching approximately ₹29.88 crore.

Business and investment fraud emerged as the most damaging category, accounting for losses of ₹22.39 crore involving 127 victims. Investigators noted that fraudsters often lure professionals with promises of high returns, fake investment opportunities, and deceptive business schemes.

Authorities also reported a wide range of other cyber offences affecting doctors, including digital arrest scams, identity theft, impersonation fraud, fake advertisements, job-related scams, insurance fraud, cryptocurrency fraud, UPI-related cheating, matrimonial scams, and sextortion cases.

Authorities Stress Importance of Rapid Reporting

The Telangana Cyber Security Bureau urged victims to report cybercrime incidents immediately, especially during the critical “golden hour” after a fraudulent transaction occurs.

Officials explained that timely complaints through the national cybercrime helpline 1930 and the official cybercrime reporting portal can significantly improve the chances of freezing suspicious transactions and recovering stolen funds.

The bureau further warned that cybercriminals are employing increasingly advanced techniques to deceive victims, making awareness and quick action more important than ever.

Medical Associations Join Awareness Drive

Representatives from associations of paediatricians, cardiologists, dentists, orthopaedic surgeons, gynaecologists, and hospital administrators participated in the discussions. The groups pledged to work closely with authorities to spread cybersecurity awareness through hospitals, clinics, medical conferences, and professional training programmes.

Officials believe that expanding cyber awareness among healthcare professionals will play a key role in reducing financial fraud and strengthening digital security across the state’s medical community.

As cyber threats continue to evolve, law enforcement agencies are encouraging doctors and other professionals to remain cautious when responding to investment offers, unknown communications, and requests for sensitive financial information online.

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