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Is CBN The Fountain Of Youth? Here’s What A Recent Study Found

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Can the cannabinoid CBN help slow aging in brain cells, and protect the brain from age-related conditions?

It turns out that one of the ways your brain cells can remain sharp over time is with a steady dose of CBD. Some days back, the brilliant scientists at Salk revealed this fantastic discovery. They said that CBN, a minor and relatively unknown cannabinoid, has the potential to protect brain cells from the adverse impact of aging.

Research on medical cannabis has been going on for many decades. For the most of this duration, scientists have focused more on the therapeutic properties of major cannabinoid compounds (i.e. THC and CBD). Minor cannabinoids like cannabinol (CBN), cannabidiolic acid (CBDA), cannabigerolic acid (CBGA), acid (CBNA), cannabidivarin (CBDV), tetrahydrocannabivarin (THCV), cannabigerol (CBG), and acid (THCA) have been given less attention. We’ve begun to observe an influx of research into these minor compounds.

cannabis brain
Photo by Feodora Chiosea/Getty Images

Scientists say that these minor cannabinoids have more to offer medically. New researchers are investigating how these compounds are broken down and their interactions with the endocannabinoid system, emphasizing their effects on the brain.

Cannabinol and the Human Brain

Cannabinol has a similar molecular structure to THC, the major difference being that it is not psychoactive. The non-psychoactive property of the compound has caused it to be less regulated by federal agencies. The Salk researchers were pleased to announce their latest influential studies, which have established that cannabinol (CBN) positively impacts the brain. In the last decade, scientists around the world have tried to investigate the medical potential of CBN. However, the federal prohibition of the cannabis plant has limited these studies.

The primary pathway to the death of cells is through oxidative injuries. This is usually followed by neurologic disorders in aged people. This new study describes how cannabinol can shield brain cells, also called nerve cells, from the damaging effects of this pathway. The findings of this trial have been published in the online Free Radical Biology and Medicine journal. The detailed report implies that cannabinol could be an effective drug to treat or manage age-induced neurodegenerative diseases like Alzheimer’s. Scientists suggest that CBN has a high potential for protecting nerve cells as a person ages.

Salk Study Research

Professor Pamela Maher, senior author and head of Salk’s Cellular Neurobiology Laboratory, said her team had discovered the anti-neurodegenerative effects of cannabinol. She mentioned that her team studied how the cannabinoid shields nerve cells from oxidative stress and death, which are major contributors to the onset of dementia and Alzheimer’s diseases.

According to Neuroscience News, Maher and her team of brilliant researchers believe this discovery would lead to the development of new drugs and treatment plans to treat various neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s. Maher’s lab had studied the use of cannabinol in the past, and this recent investigation was done to build on the first discoveries. In the preliminary research, the team found out about the protective properties of CBN on the brain and how CBN could be used to derive drugs for neurological diseases.

This recent study focused more on how CBN functions in the body. During this study, Salk scientists took into account the oxytosis and ferroptosis processes, a major contributing factor to aging and diseased brain cells. The oxytosis, or ferroptosis process occurs in aging brains. The mechanism is induced by the gradual loss of glutathione, an antioxidant, as a person ages. It results in prominent damage or death to neural cells through lip oxidation. The trial began by administering CBN to nerve cells to observe how they limit oxidative action. The scientists then proceeded to propose a different mechanism to induce oxidative damage.

Study Observations  

Following testing healthy and damaged brain cells with cannabinol, the following observations were made. The report stated that the administered cannabinol protected the nerve cells. They also observed that the mitochondria, a cell’s powerhouse, were protected from oxidative damage.

The mitochondria in healthy cells were compared with those in damaged cells. Maher and her team found that the mitochondria in the damaged cell appeared to be folded up in a round shape to shield it from more damage. These scrunched-up powerhouses are frequently noticed within the brain cells of Alzheimer’s and Parkinson’s patients.

Treating Dementia With Cannabis: What Patients And Caregivers Should Know
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On the other hand, the healthy cells appropriately housed functioning mitochondria. The powerhouse in these cells remained in its regular, non-folded form.

Maher wrote that her team successfully showed that cannabinol could contribute to maintaining mitochondria in nerve cells. She added that the protective effects of CBN urged the proper functioning of the powerhouse.

More Information

Zhinin Liang, co-author and postdoctoral fellow, says that smoke evidence shows that cannabinol is safe for human and animal consumption. This can be linked to the absence of psychotropic effects after CBN is consumed. The researcher said that CBN works on specific cells in the body while delivering therapeutic effects.

Maher also noted that her team’s findings reveal implications for other neurodegenerative diseases connected to glutathione loss. The dysfunction of a nerve cell’s powerhouse results in further damage to nearby tissues. The potential of CBN to heal and maintain functions in a powerhouse suggests that it could also be used to treat other parts of the body besides the brain. This opens the floor for further research beyond the context of neurodegenerative conditions. The next agenda item for the team is to reproduce the above study in a preclinical mouse model.

Other researchers that contributed to the success of this study include Brendan Duggan from the University of California, Antonio Currais, David Schubert, Devin Kepchiaz, and David Soriano-Castell Salk. The Paul F. Glenn Center for Biology of Aging Research at Salk, the Shikey Foundation, the University of California, The Bundy Foundation, and the National Health Institute provided funding.

Bottom Line

Salk’s CBN research points out the need for more investigations into lesser-studied cannabinoids. Most of these minor cannabinoids have shown little therapeutic potential in the limited levels of research done.

Some of the therapeutic benefits possessed by CBN, as suggested by anecdotal evidence, include pain relief, stress relief, and anti-inflammatory effects. This buttresses Maher’s point that further comprehensive research must be done.

Source: https://420-reports.com/wp-admin/post.php?post=4857&action=edit

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Jio’s 1,600-Satellite LEO Constellation Gets Technical Green Light

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Reliance Jio has crossed a significant milestone in its space connectivity ambitions after its proposal to deploy a Low Earth Orbit (LEO) satellite constellation of around 1,600 satellites received a positive technical assessment from the Indian National Space Promotion and Authorisation Centre (IN-SPACe).

The evaluation, conducted jointly by IN-SPACe, the Indian Space Research Organisation (ISRO), and the Wireless Planning and Coordination (WPC) wing of the Department of Telecommunications, reportedly concluded that Jio’s proposed system meets the required technical standards and is comparable to leading global satellite broadband networks.

India’s Indigenous LEO Satellite Vision

Under the proposal, Reliance Jio plans to deploy between 1,600 and 1,650 satellites in Low Earth Orbit at an altitude of around 650 kilometres.

The planned constellation is expected to provide high-speed satellite connectivity across India, with approximately 32 satellites visible from any location at a given time. The company aims to roll out the network within the next two to three years, subject to regulatory approvals.

According to industry estimates, the satellite system could deliver 4.5 to 5 terabits per second (Tbps) of total data capacity, making it one of the largest satellite broadband projects proposed in India.

The project is expected to require an investment of $10–15 billion (approximately ₹95,000 crore to ₹1.42 lakh crore), reflecting the scale of infrastructure needed for satellite manufacturing, launches, ground stations, and user terminals.

Regulatory Process Moves Forward

Following the successful technical review, the proposal is expected to move into the next phase of regulatory approvals.

The government may now assist Jio in securing orbital slots, coordinating spectrum usage, and filing applications with the International Telecommunication Union (ITU), the global body responsible for managing satellite orbit and frequency allocations.

Obtaining orbital rights remains a critical step, as Low Earth Orbit has become increasingly competitive due to the growing number of satellite broadband projects being planned worldwide.

Officials also indicated that the proposed satellite architecture has been designed to coexist with future Indian LEO constellations, allowing multiple domestic operators to share orbital resources efficiently.

Broadband, Mobile Connectivity, and Strategic Applications

Jio plans to use the satellite network to provide a range of communication services, including satellite broadband, mobile backhaul, enterprise connectivity, and direct-to-device (D2D) satellite communication, particularly in remote and underserved regions where conventional telecom infrastructure is limited.

The company also intends to establish 20 to 22 ground stations across India to support network operations.

Apart from commercial telecommunications, officials have highlighted the project’s potential strategic importance. A domestically developed satellite constellation could strengthen India’s communication infrastructure, reduce dependence on foreign satellite operators, and support national security requirements.

Reports suggest preliminary discussions are underway regarding the possibility of integrating defence-related payloads into some satellites, enabling both civilian and strategic use.

Major Step for India’s Space and Telecom Sectors

Industry analysts view the technical clearance as an important milestone in India’s expanding private space ecosystem. If Jio secures the remaining regulatory approvals and international orbital clearances, the project could become the country’s first large-scale indigenous LEO satellite broadband network.

The initiative also aligns with India’s broader efforts to expand digital connectivity while strengthening its presence in the global satellite communications market.

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Alleged Crores Pharma Scam Mastermind Arrested from Surat

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After evading law enforcement for nearly 13 years, an accused linked to a large-scale pharmaceutical fraud case has been arrested by Delhi Police from Surat, Gujarat. The suspect is alleged to have orchestrated a series of financial scams involving fake identities, forged documents, and dishonoured cheques used to procure high-value pharmaceutical raw materials.

Authorities say the accused, identified as Himmat Singh Lodha, is believed to have defrauded multiple pharmaceutical companies in Delhi of goods worth approximately ₹98 lakh before disappearing and remaining underground for years.

Fake Business Deals and Dishonoured Cheques Used in Fraud

Investigators claim the accused posed as a legitimate pharmaceutical trader and placed bulk orders for expensive drug ingredients, offering post-dated cheques as payment security.

In one documented case from 2013, he allegedly obtained around 550 kilograms of Gliclazide, a diabetes-related pharmaceutical ingredient, valued at over ₹26 lakh. When suppliers attempted to encash the cheques, they were reportedly returned with the remark “account closed.”

Following the transaction, the accused allegedly vacated his office and rented residence and disappeared without settling payments. He was later declared a proclaimed offender in 2016 after repeatedly failing to appear before court proceedings. Authorities had also issued a reward for information leading to his arrest.

Multiple Identities and Repeated Fraud Pattern

Police investigations further link the accused to another cheating case dating back to 2012, where he allegedly used a fake identity, “Kailash Jain,” to obtain a large consignment of Ambroxol HCL, a pharmaceutical compound used in cough medications. The value of that consignment was estimated at around ₹72 lakh.

Officials believe the accused followed a consistent modus operandi—posing as a credible businessman, securing high-value goods on deferred payment terms, and then disappearing after delivery while shutting down business operations.

Investigators suspect that forged business records, fake company credentials, and fabricated financial histories were used to build trust with suppliers and gain access to expensive raw materials.

Multi-State Surveillance Leads to Arrest in Surat

A special Crime Branch team tracked the accused through coordinated surveillance efforts across multiple cities, including Mumbai, Ahmedabad, and Surat. After nearly a month of technical monitoring and intelligence gathering, officials located and arrested him from a residential area in Surat.

Authorities also revealed that the accused had been involved in property-related activities while staying under the radar to avoid detection.

Growing Threat of Corporate Identity Fraud

The case highlights a rising trend of organised financial fraud targeting industries that rely heavily on trust-based transactions and deferred payments. Experts note that criminals increasingly exploit gaps in corporate verification systems by using fake GST registrations, temporary offices, and forged documentation to appear legitimate.

Cybercrime and financial fraud specialists warn that such schemes are becoming more complex with the widespread availability of digital business tools, making it easier to create convincing but fraudulent corporate identities.

Experts Urge Stronger Due Diligence in High-Value Transactions

Experts, including former IPS officer and cybercrime specialist Prof. Triveni Singh, emphasize the need for stricter verification procedures in commercial dealings. He noted that relying solely on paperwork or digital business profiles can expose companies to significant financial risk.

Authorities and industry experts recommend physical verification of business operations, bank account validation, and detailed background checks before engaging in high-value or deferred-payment transactions—particularly in sectors like pharmaceuticals, where single consignments can involve transactions worth crores.

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EU Pressure Builds on Google as Regulators Face Calls for Massive Fine Over Search Practices

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A growing coalition of European industry groups is intensifying pressure on regulators to take decisive action against Google over allegations of unfair search practices that could reshape competition rules across the region’s digital economy.

Investigation Under Digital Markets Act Gains Momentum

The case is being examined by the European Commission under the European Union’s landmark Digital Markets Act (DMA), introduced to curb the dominance of major technology platforms and ensure fair competition.

Launched in March 2024, the investigation focuses on whether Google has been prioritising its own services in search results, potentially disadvantaging rival businesses that rely on online visibility to reach customers.

Industry Groups Demand Swift Action

Several prominent European organizations have jointly urged regulators to conclude the probe without further delay. They argue that prolonged investigations allow alleged anti-competitive practices to continue, putting European companies—especially startups—at a disadvantage.

Signatories include the European Publishers Council, the European Magazine Media Association, the European Tech Alliance, and EU Travel Tech.

In a joint statement, these groups warned that delays in enforcement are affecting innovation, profitability, and growth prospects for regional businesses competing in digital markets.

Google Denies Allegations

Google has rejected claims of bias, stating that its search algorithms are designed to deliver the most relevant and useful results to users. The company has also proposed adjustments to address regulatory concerns.

However, critics argue that these changes are insufficient and fail to address the core issue of market dominance.

Potential Billion-Euro Penalties

If found in violation of the DMA, Google could face significant financial penalties. Under EU rules, fines can reach a substantial percentage of a company’s global turnover, potentially amounting to billions of euros.

Regulators may also impose corrective measures requiring changes to business practices, which could have long-term implications for how digital platforms operate in Europe.

Wider Implications for Big Tech

The case highlights ongoing tensions between European regulators and major U.S. technology firms. In recent years, the EU has taken a more aggressive stance in enforcing competition laws, aiming to create a level playing field for local businesses.

A final ruling against Google could set a major precedent, influencing future enforcement actions and shaping the regulatory landscape for global tech companies operating within Europe.

As scrutiny intensifies, the outcome of the investigation is expected to play a critical role in defining the future of digital competition across the European Union.

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