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Cal NORML Warns of Potential THC-O Acetate Risk

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A study shows both THC-O and vitamin E acetate may convert into a dangerous lung toxin when they are heated in a vape pen.

New data shows a potential problem with vaping THC-O acetate, and the reasons are worthy of concern. The National Organization for the Reform of Marijuana Laws (NORML) branch in California, Cal NORML, issued a warning on Jan. 9 about a study that shows a significant risk for people who vape products containing THC-O acetate.

First published in the Journal of Medical Toxicology on Dec. 12, 2022, a team of researchers led by Neal L. Benowitz discovered a link between THC-O acetate and significant danger to the lungs. THC-O acetate shares structural similarities with vitamin-E acetate—an additive that becomes dangerous to the lungs when converted by heat.

According to the California Department of Public Health, the 2019-20 outbreak of EVALI lung disease sickened and hospitalized 249 Californians—five of them fatally. On Nov. 15, 2019, the Centers for Disease Control and Prevention (CDC) confirmed that vitamin E acetate is the likely culprit for EVALI. Vitamin E acetate also produces carcinogens such as alkenes and benzene when heated.

When heated in a vape pen, both substances—vitamin E acetate and THC-O Acetate—produce ketene, a “highly potent lung toxicant.”  

“We put out the press release specifically because of a study showing that vaporizing vitamin E acetate was similar to THC-O acetate,” Cal NORML Director Dale Gieringer told High Times.

 “Apparently when heated up, it produces a serious lung toxin called ketene.”

As cannabis consumers, we often have to filter through anti-cannabis hysteria, but certain risks hold weight when products aren’t regulated properly. Usually vaping dangers arise when random thickeners and unvetted compounds are added.

Gieringer added, “We have a lot of concerns about some of these other new cannabinoids that are being synthesized from hemp, which are brand new and never been tested in human subjects before. Some of them are advertised as being way more potent than THC. THC-O acetate is being advertised as three times more potent than delta-9. THCP is being advertised as having 30 times the binding power to receptors as THC. That kind of reaction sets off a lot of concerns with us. 

“These compounds have never been found in nature before—being made by fairly amateurish underground hemp chemists—raise a lot of concern.”

Gieringer added that delta-8 THC isn’t his primary concern, given there is slightly more known about the compound, but it’s contaminants and other new cannabinoids he’s most worried about, mostly due to the unknowns: THCP, THCjd. THC-H, THC-B, HHC, and Delta-10 THC. 

Cal NORML reports that the sale of psychoactive hemp derivatives was recently deemed legal under federal law by a Ninth Circuit Court decision (AK Futures v. Boyd Street Distro). That’s up for debate though, given that synthetic cannabinoids can be considered illegal under the Federal Analogue Act. 

Under the 2018 federal Farm Bill, cannabis with less that 0.3% THC is legal to grow, and its products can be sold nationally, but the THC often exceeds the limit regardless.

California’s industrial hemp law, which is overseen by the California Department of Public Health (CDPH), currently disallows the sale of hemp products with active cannabinoids other than CBD.

THC-O acetate begins as hemp-derived CBD and goes through a chemical process. Going beyond how cannabinoids like delta-8 THC are processed from CBD, acetic anhydride is added to the mixture, making it an acetate.

THC-O is believed to be three times as potent as delta-9 THC—the naturally occurring cannabinoid most of us are used to.

“Cal NORML strongly advises consumers to avoid hemp products with psychoactive cannabinoids, especially novel ones stronger than THC, whose safety is particularly suspect. CBD products may be safely obtained from state-registered industrial hemp product manufacturers, whose products must be tested for safety and cannabinoid content,” the release reads. “Under state law, hemp products should have a batch number and a label, website, QR code or barcode linking to the laboratory test results that state the levels of cannabinoids, total THC, and presence of contaminants, as well as the address and phone number of the manufacturer. Violations can be reported to CDPH.

Cal NORML adds that the less common cannabinoids that are deemed safe for human use are CBN, CBG, CBC, THCV, THC-A, CBD-A, and Delta-8 THC.

Source: https://hightimes.com/health/cal-norml-warns-of-potential-thc-o-acetate-risk/

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Alleged Crores Pharma Scam Mastermind Arrested from Surat

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After evading law enforcement for nearly 13 years, an accused linked to a large-scale pharmaceutical fraud case has been arrested by Delhi Police from Surat, Gujarat. The suspect is alleged to have orchestrated a series of financial scams involving fake identities, forged documents, and dishonoured cheques used to procure high-value pharmaceutical raw materials.

Authorities say the accused, identified as Himmat Singh Lodha, is believed to have defrauded multiple pharmaceutical companies in Delhi of goods worth approximately ₹98 lakh before disappearing and remaining underground for years.

Fake Business Deals and Dishonoured Cheques Used in Fraud

Investigators claim the accused posed as a legitimate pharmaceutical trader and placed bulk orders for expensive drug ingredients, offering post-dated cheques as payment security.

In one documented case from 2013, he allegedly obtained around 550 kilograms of Gliclazide, a diabetes-related pharmaceutical ingredient, valued at over ₹26 lakh. When suppliers attempted to encash the cheques, they were reportedly returned with the remark “account closed.”

Following the transaction, the accused allegedly vacated his office and rented residence and disappeared without settling payments. He was later declared a proclaimed offender in 2016 after repeatedly failing to appear before court proceedings. Authorities had also issued a reward for information leading to his arrest.

Multiple Identities and Repeated Fraud Pattern

Police investigations further link the accused to another cheating case dating back to 2012, where he allegedly used a fake identity, “Kailash Jain,” to obtain a large consignment of Ambroxol HCL, a pharmaceutical compound used in cough medications. The value of that consignment was estimated at around ₹72 lakh.

Officials believe the accused followed a consistent modus operandi—posing as a credible businessman, securing high-value goods on deferred payment terms, and then disappearing after delivery while shutting down business operations.

Investigators suspect that forged business records, fake company credentials, and fabricated financial histories were used to build trust with suppliers and gain access to expensive raw materials.

Multi-State Surveillance Leads to Arrest in Surat

A special Crime Branch team tracked the accused through coordinated surveillance efforts across multiple cities, including Mumbai, Ahmedabad, and Surat. After nearly a month of technical monitoring and intelligence gathering, officials located and arrested him from a residential area in Surat.

Authorities also revealed that the accused had been involved in property-related activities while staying under the radar to avoid detection.

Growing Threat of Corporate Identity Fraud

The case highlights a rising trend of organised financial fraud targeting industries that rely heavily on trust-based transactions and deferred payments. Experts note that criminals increasingly exploit gaps in corporate verification systems by using fake GST registrations, temporary offices, and forged documentation to appear legitimate.

Cybercrime and financial fraud specialists warn that such schemes are becoming more complex with the widespread availability of digital business tools, making it easier to create convincing but fraudulent corporate identities.

Experts Urge Stronger Due Diligence in High-Value Transactions

Experts, including former IPS officer and cybercrime specialist Prof. Triveni Singh, emphasize the need for stricter verification procedures in commercial dealings. He noted that relying solely on paperwork or digital business profiles can expose companies to significant financial risk.

Authorities and industry experts recommend physical verification of business operations, bank account validation, and detailed background checks before engaging in high-value or deferred-payment transactions—particularly in sectors like pharmaceuticals, where single consignments can involve transactions worth crores.

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EU Pressure Builds on Google as Regulators Face Calls for Massive Fine Over Search Practices

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A growing coalition of European industry groups is intensifying pressure on regulators to take decisive action against Google over allegations of unfair search practices that could reshape competition rules across the region’s digital economy.

Investigation Under Digital Markets Act Gains Momentum

The case is being examined by the European Commission under the European Union’s landmark Digital Markets Act (DMA), introduced to curb the dominance of major technology platforms and ensure fair competition.

Launched in March 2024, the investigation focuses on whether Google has been prioritising its own services in search results, potentially disadvantaging rival businesses that rely on online visibility to reach customers.

Industry Groups Demand Swift Action

Several prominent European organizations have jointly urged regulators to conclude the probe without further delay. They argue that prolonged investigations allow alleged anti-competitive practices to continue, putting European companies—especially startups—at a disadvantage.

Signatories include the European Publishers Council, the European Magazine Media Association, the European Tech Alliance, and EU Travel Tech.

In a joint statement, these groups warned that delays in enforcement are affecting innovation, profitability, and growth prospects for regional businesses competing in digital markets.

Google Denies Allegations

Google has rejected claims of bias, stating that its search algorithms are designed to deliver the most relevant and useful results to users. The company has also proposed adjustments to address regulatory concerns.

However, critics argue that these changes are insufficient and fail to address the core issue of market dominance.

Potential Billion-Euro Penalties

If found in violation of the DMA, Google could face significant financial penalties. Under EU rules, fines can reach a substantial percentage of a company’s global turnover, potentially amounting to billions of euros.

Regulators may also impose corrective measures requiring changes to business practices, which could have long-term implications for how digital platforms operate in Europe.

Wider Implications for Big Tech

The case highlights ongoing tensions between European regulators and major U.S. technology firms. In recent years, the EU has taken a more aggressive stance in enforcing competition laws, aiming to create a level playing field for local businesses.

A final ruling against Google could set a major precedent, influencing future enforcement actions and shaping the regulatory landscape for global tech companies operating within Europe.

As scrutiny intensifies, the outcome of the investigation is expected to play a critical role in defining the future of digital competition across the European Union.

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Amazon Faces Potential Criminal Trial in Italy Over €1.2 Billion Tax Evasion Allegations

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Milan: U.S. tech giant Amazon is facing the prospect of a major legal showdown in Italy, after prosecutors in Milan formally requested a court to move forward with criminal proceedings over alleged tax evasion totaling approximately ₹12,500 crore (€1.2 billion).

The case targets Amazon’s European division along with four senior executives, marking one of the most significant tax-related investigations involving a global e-commerce platform in Europe.

Trial Push Despite Multi-Million Euro Settlement

The move comes even after Amazon reached a financial settlement with Italian tax authorities in December, agreeing to pay around ₹5,500 crore (€527 million), including interest, to resolve part of the dispute.

Typically, such settlements lead to the closure of criminal investigations. However, Milan prosecutors have opted to proceed, signaling a tougher stance on alleged corporate tax violations.

A preliminary hearing is expected in the coming months, where a judge will decide whether to formally indict the company and its executives or dismiss the case.

Allegations of VAT Evasion Through Marketplace Sellers

At the center of the investigation are claims that Amazon’s platform enabled non-European Union sellers to avoid paying value-added tax (VAT) on goods sold to Italian consumers between 2019 and 2021.

Prosecutors allege that the company’s marketplace structure allowed thousands of foreign vendors—many reportedly based in China—to operate without fully disclosing their identities or tax obligations. This, authorities argue, led to substantial VAT losses for the Italian government.

Under Italian law, online platforms facilitating sales can be held partially liable if third-party sellers fail to comply with tax requirements, a key point in the prosecution’s case.

Italian Government Named as Affected Party

In their filing, prosecutors identified Italy’s Economy Ministry as the injured party, citing significant financial damage resulting from the alleged tax evasion.

Legal experts say the outcome of the case could have wide-ranging implications across the European Union, where VAT systems are harmonized and similar compliance rules apply to digital marketplaces.

Multiple Investigations Add to Pressure

The VAT probe is just one of several legal challenges facing Amazon in Italy. The European Public Prosecutor’s Office is reportedly examining additional tax-related issues covering more recent years.

Meanwhile, Milan authorities are pursuing separate investigations into alleged customs fraud linked to imports from China and whether Amazon maintained an undeclared “permanent establishment” in Italy—potentially exposing it to higher tax liabilities.

In a separate regulatory action, Italy’s data protection authority recently ordered an Amazon unit to stop using personal data from over 1,800 employees at a warehouse near Rome.

Amazon Denies Allegations

Amazon has consistently denied wrongdoing and indicated it will strongly contest the allegations in court if the case proceeds. The company has also warned that prolonged legal uncertainty could impact investor confidence and Italy’s appeal as a destination for international business.

Broader Impact on Europe’s Digital Economy

If the case moves to trial, it could become a landmark moment for the regulation of global e-commerce platforms in Europe. Governments across the region are increasingly scrutinizing how digital marketplaces handle tax compliance, especially in cross-border transactions.

With online retail continuing to expand, regulators are under mounting pressure to ensure that multinational platforms and third-party sellers adhere to the same tax rules as traditional businesses.

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