Business
New THC-CBD Pill for MS and Huntington’s Disease May Be First to Benefit from Biden’s New Marijuana Research Bill
MMJ’s cannabis pill for multiple sclerosis and Huntington’s Disease may be up next!
The MMJ trifecta of firms, in partnership with a specialized pharmaceutical soft gelatin production firm, has completed production of its CBD, THC capsule medicine based on compounds in the cannabis plant. The company will conduct clinical trials on its unique pharmaceutical to demonstrate its safety, efficacy, and treatment for individuals with Huntington’s disease (HD) and multiple sclerosis (MS).
Once FDA-approved for usage in clinical trials, MMJ will be the only firm offering a CBD and THC pill that will be thoroughly tested in clinical studies. It also implies that this plant-based, non-synthetic, highly purified form of CBD and THC is produced following the FDA’s current Good Manufacturing Practices guidelines.
“MMJ International Holdings has pushed carefully for the past five years to formulate the capsule and log in all of the evidence required by the FDA for approval,” said Dr. Elio Mariani, MMJ’s CEO. The president of MMJ, Duane Boise, also added that among MMJ’s lead treatments are MMJ-001 and MMJ-002. Both capsules are based on a colloidal solution of highly purified extracts of THC, CBD, and other compounds from the cannabis plant.
MMJ-001 is being evaluated as a therapy for muscle stiffness (spasticity) in individuals with multiple sclerosis. MMJ-002 is an experimental therapy for Huntington’s-related chorea (a neurological disorder with the characteristic symptom of involuntary jerking movements). The US Food and Medication Administration has designated MMJ-002 as an orphan drug (FDA).
“MMJ’s clinical trials will provide data to the FDA on patient dose, safety, and efficacy to establish that cannabis can cure critical tremors, a neurological condition that results in involuntary shaking,” Duane Boise said. “We are confident that our MMJ oral gel cap medication, which contains the marijuana plant’s distinctive pharmacological qualities, will be authorized by the FDA as an effective and safe drug,” Tim Moynahan, board chairman, added.
MMJ recently received DEA approval to import cannabis-based goods into the United States, a process that requires the collaboration of various government agencies, including the FDA, Health Canada, and the United States Drug Enforcement Agency (DEA). In addition, the company recently received DEA clearance for a schedule 1 cannabis experimental lab and is seeking final DEA approval for their API Bulk Manufacturing Registration to produce cannabis plants.
“Our competent team was working within the DEA and FDA requirements to acquire all clearances,” Boise stated. “MMJ may now move forward with developing our cannabis-derived, natural extracts for our oral gel capsule medications in clinical studies in the United States.”
The Marijuana Research and Expansion Act
In related news, President Biden signed the Marijuana Research and Expansion Act into law. This will speed up researchers’ bids for DEA schedule 1 registration authorization to undertake these trials. After seven hard years of waiting, the MMJ group of firms can finish their mission of performing clinical studies on Huntington’s Disease and Multiple Sclerosis. MMJ has received FDA Orphan Designation for its Huntington’s disease clinical trials.
The measure explicitly authorizes the Drug Enforcement Administration (DEA) to adopt specific procedures to register;
- Practitioners to conduct marijuana research and
- Producers supply marijuana for the research.
The measure authorizes MMJ businesses to possess, manufacture, sell, or dispense cannabidiol (CBD) or marijuana (THC) for medical research purposes. The measure also states that the US attorney general will have 2 months to approve or request additional data from the cannabis research applicant. It also makes it easier for MMJ researchers to obtain more significant amounts of cannabis.
The company’s CEO, Dr. Elio Mariani, claimed, “In the instance of MMJ, the company is developing a soft gel pill to treat the symptoms of Huntington’s Disease and Multiple Sclerosis. Other researchers could potentially use the gel capsule composition in clinical trials “.
The DEA MOA has been issued, and MMJ is on pace to earn a vertically integrated Schedule 1 cannabis production and cultivation license. The firm is also nearing the completion of its state-of-the-art marijuana center of excellence in Rhode Island. The MOA specifies how the firm plans to conduct business with the DEA when a few minor changes are made following the DEA’s requirements and the final registration is approved.
“These permits fall under severe DEA monitoring and require stringent regulations of operation, all of which MMJ has met,” said Jorge Jimenez, MMJ’s head of regulatory compliance. This year, MMJ was granted a schedule 1 analytical lab license. MMJ has teamed with the University of Connecticut since Schedule 1 licenses are generally issued to cultivators linked with an academic institution for research and development.
“MMJ is committed to furthering its research and development through a method that is in accordance with the government’s aim to prioritize public health, support innovation, and promote customer trust,” commented Duane Boise.
MMJ International Holdings Milestones
MMJ International Holdings recently secured a DEA license to import its proprietary cannabis extracts into the United States for possible cures for Multiple Sclerosis and Huntington’s Disease. After a significant amount of effort, the team has reached vital milestones, which include:
- Identified unique cannabis strains for high levels of CBD and THC.
- All necessary testing on dried and raw plant “buds” was completed following the FDA Botanical Drug Development Guidance.
- Developed a unique extraction method to maximize the levels of both THC and CBD
- Analyzed every component present in the extracts for other plant extracts and endocannabinoids.
- Chemical and physical stability data for every extract have been established (THC and CBD)
- Received DEA approval to import extracts from non-US countries to the US.
- Contract with a pharmaceutical business to formulate soft gelatin capsules with a predetermined THC/CBD ratio for phase 2 and 3 clinical trials.
- MMJ BioPharma Cultivation has completed arrangements with a sovereign Native American Indian country for a DEA-approved “grow” of the marijuana plant for pharmaceutical, academic, and research companies.
- The FDA granted Orphan Drug Approval for their patented soft gelatin dose formulation having a set ratio of THC and CBD for the clinical research of Huntington’s Chorea.
Conclusion
MMJ acknowledges the public’s interest in cannabis-derived and cannabis substances. The MMJ team is working hard to fill information gaps about their products’ chemistry, quality, and safety. “We are committed to developing our cannabis cultivation, lab formulations, and clinical studies in accordance with our purpose of prioritizing public health, fostering innovation, and promoting customer trust,” Duane Boise stated.
Business
Jio’s 1,600-Satellite LEO Constellation Gets Technical Green Light
Reliance Jio has crossed a significant milestone in its space connectivity ambitions after its proposal to deploy a Low Earth Orbit (LEO) satellite constellation of around 1,600 satellites received a positive technical assessment from the Indian National Space Promotion and Authorisation Centre (IN-SPACe).
The evaluation, conducted jointly by IN-SPACe, the Indian Space Research Organisation (ISRO), and the Wireless Planning and Coordination (WPC) wing of the Department of Telecommunications, reportedly concluded that Jio’s proposed system meets the required technical standards and is comparable to leading global satellite broadband networks.
India’s Indigenous LEO Satellite Vision
Under the proposal, Reliance Jio plans to deploy between 1,600 and 1,650 satellites in Low Earth Orbit at an altitude of around 650 kilometres.
The planned constellation is expected to provide high-speed satellite connectivity across India, with approximately 32 satellites visible from any location at a given time. The company aims to roll out the network within the next two to three years, subject to regulatory approvals.
According to industry estimates, the satellite system could deliver 4.5 to 5 terabits per second (Tbps) of total data capacity, making it one of the largest satellite broadband projects proposed in India.
The project is expected to require an investment of $10–15 billion (approximately ₹95,000 crore to ₹1.42 lakh crore), reflecting the scale of infrastructure needed for satellite manufacturing, launches, ground stations, and user terminals.
Regulatory Process Moves Forward
Following the successful technical review, the proposal is expected to move into the next phase of regulatory approvals.
The government may now assist Jio in securing orbital slots, coordinating spectrum usage, and filing applications with the International Telecommunication Union (ITU), the global body responsible for managing satellite orbit and frequency allocations.
Obtaining orbital rights remains a critical step, as Low Earth Orbit has become increasingly competitive due to the growing number of satellite broadband projects being planned worldwide.
Officials also indicated that the proposed satellite architecture has been designed to coexist with future Indian LEO constellations, allowing multiple domestic operators to share orbital resources efficiently.
Broadband, Mobile Connectivity, and Strategic Applications
Jio plans to use the satellite network to provide a range of communication services, including satellite broadband, mobile backhaul, enterprise connectivity, and direct-to-device (D2D) satellite communication, particularly in remote and underserved regions where conventional telecom infrastructure is limited.
The company also intends to establish 20 to 22 ground stations across India to support network operations.
Apart from commercial telecommunications, officials have highlighted the project’s potential strategic importance. A domestically developed satellite constellation could strengthen India’s communication infrastructure, reduce dependence on foreign satellite operators, and support national security requirements.
Reports suggest preliminary discussions are underway regarding the possibility of integrating defence-related payloads into some satellites, enabling both civilian and strategic use.
Major Step for India’s Space and Telecom Sectors
Industry analysts view the technical clearance as an important milestone in India’s expanding private space ecosystem. If Jio secures the remaining regulatory approvals and international orbital clearances, the project could become the country’s first large-scale indigenous LEO satellite broadband network.
The initiative also aligns with India’s broader efforts to expand digital connectivity while strengthening its presence in the global satellite communications market.
Business
Alleged Crores Pharma Scam Mastermind Arrested from Surat
After evading law enforcement for nearly 13 years, an accused linked to a large-scale pharmaceutical fraud case has been arrested by Delhi Police from Surat, Gujarat. The suspect is alleged to have orchestrated a series of financial scams involving fake identities, forged documents, and dishonoured cheques used to procure high-value pharmaceutical raw materials.
Authorities say the accused, identified as Himmat Singh Lodha, is believed to have defrauded multiple pharmaceutical companies in Delhi of goods worth approximately ₹98 lakh before disappearing and remaining underground for years.
Fake Business Deals and Dishonoured Cheques Used in Fraud
Investigators claim the accused posed as a legitimate pharmaceutical trader and placed bulk orders for expensive drug ingredients, offering post-dated cheques as payment security.
In one documented case from 2013, he allegedly obtained around 550 kilograms of Gliclazide, a diabetes-related pharmaceutical ingredient, valued at over ₹26 lakh. When suppliers attempted to encash the cheques, they were reportedly returned with the remark “account closed.”
Following the transaction, the accused allegedly vacated his office and rented residence and disappeared without settling payments. He was later declared a proclaimed offender in 2016 after repeatedly failing to appear before court proceedings. Authorities had also issued a reward for information leading to his arrest.
Multiple Identities and Repeated Fraud Pattern
Police investigations further link the accused to another cheating case dating back to 2012, where he allegedly used a fake identity, “Kailash Jain,” to obtain a large consignment of Ambroxol HCL, a pharmaceutical compound used in cough medications. The value of that consignment was estimated at around ₹72 lakh.
Officials believe the accused followed a consistent modus operandi—posing as a credible businessman, securing high-value goods on deferred payment terms, and then disappearing after delivery while shutting down business operations.
Investigators suspect that forged business records, fake company credentials, and fabricated financial histories were used to build trust with suppliers and gain access to expensive raw materials.
Multi-State Surveillance Leads to Arrest in Surat
A special Crime Branch team tracked the accused through coordinated surveillance efforts across multiple cities, including Mumbai, Ahmedabad, and Surat. After nearly a month of technical monitoring and intelligence gathering, officials located and arrested him from a residential area in Surat.
Authorities also revealed that the accused had been involved in property-related activities while staying under the radar to avoid detection.
Growing Threat of Corporate Identity Fraud
The case highlights a rising trend of organised financial fraud targeting industries that rely heavily on trust-based transactions and deferred payments. Experts note that criminals increasingly exploit gaps in corporate verification systems by using fake GST registrations, temporary offices, and forged documentation to appear legitimate.
Cybercrime and financial fraud specialists warn that such schemes are becoming more complex with the widespread availability of digital business tools, making it easier to create convincing but fraudulent corporate identities.
Experts Urge Stronger Due Diligence in High-Value Transactions
Experts, including former IPS officer and cybercrime specialist Prof. Triveni Singh, emphasize the need for stricter verification procedures in commercial dealings. He noted that relying solely on paperwork or digital business profiles can expose companies to significant financial risk.
Authorities and industry experts recommend physical verification of business operations, bank account validation, and detailed background checks before engaging in high-value or deferred-payment transactions—particularly in sectors like pharmaceuticals, where single consignments can involve transactions worth crores.
Business
EU Pressure Builds on Google as Regulators Face Calls for Massive Fine Over Search Practices
A growing coalition of European industry groups is intensifying pressure on regulators to take decisive action against Google over allegations of unfair search practices that could reshape competition rules across the region’s digital economy.
Investigation Under Digital Markets Act Gains Momentum
The case is being examined by the European Commission under the European Union’s landmark Digital Markets Act (DMA), introduced to curb the dominance of major technology platforms and ensure fair competition.
Launched in March 2024, the investigation focuses on whether Google has been prioritising its own services in search results, potentially disadvantaging rival businesses that rely on online visibility to reach customers.
Industry Groups Demand Swift Action
Several prominent European organizations have jointly urged regulators to conclude the probe without further delay. They argue that prolonged investigations allow alleged anti-competitive practices to continue, putting European companies—especially startups—at a disadvantage.
Signatories include the European Publishers Council, the European Magazine Media Association, the European Tech Alliance, and EU Travel Tech.
In a joint statement, these groups warned that delays in enforcement are affecting innovation, profitability, and growth prospects for regional businesses competing in digital markets.
Google Denies Allegations
Google has rejected claims of bias, stating that its search algorithms are designed to deliver the most relevant and useful results to users. The company has also proposed adjustments to address regulatory concerns.
However, critics argue that these changes are insufficient and fail to address the core issue of market dominance.
Potential Billion-Euro Penalties
If found in violation of the DMA, Google could face significant financial penalties. Under EU rules, fines can reach a substantial percentage of a company’s global turnover, potentially amounting to billions of euros.
Regulators may also impose corrective measures requiring changes to business practices, which could have long-term implications for how digital platforms operate in Europe.
Wider Implications for Big Tech
The case highlights ongoing tensions between European regulators and major U.S. technology firms. In recent years, the EU has taken a more aggressive stance in enforcing competition laws, aiming to create a level playing field for local businesses.
A final ruling against Google could set a major precedent, influencing future enforcement actions and shaping the regulatory landscape for global tech companies operating within Europe.
As scrutiny intensifies, the outcome of the investigation is expected to play a critical role in defining the future of digital competition across the European Union.
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