News
Canadian University Granted License To Study Psilocybin Mushrooms
Researchers at the University of Guelph (UG) in Ontario, Canada recently received approval to study psilocybin mushrooms.
Dr. Max Jones and Dr. Gale Bozzo, two professors at UG’s Ontario Agricultural College (Department of Plant Agriculture), received a Health Canada “dealer’s license” on Oct. 25. The license permits the cultivation of psilocybin mushrooms, and is one of the first universities in Canada to be permitted to do so.
“We are very excited about this approval as it will allow us to study these psychedelic mushrooms to better understand their biology and genetics, examine what other functional compounds they might contain, and provide well-characterized and chemically consistent material for preclinical and potentially clinical evaluation,” Jones said. He previously received a license to study cannabis back in November 2018 as well.
According to Jones, there are more than 200 species of mushrooms that can produce psilocybin. “Those species aren’t that closely related; they’re diverse,” Jones said in a press release. “So that makes scientists like me wonder: what else are these mushrooms producing? If you have 200 species producing a compound that affects the human brain, it’s likely they are producing other interesting compounds, too.”
Psilocybin therapy has become a popular treatment for conditions such as depression, addiction, obsessive-compulsive disorder, and post-traumatic stress disorder. According to Dr. Melissa Perreault, Professor in Ontario Veterinary College’s Department of Biomedical Sciences and another researchers involved with the study, there’s a specific function that they’re hoping to examine. “There are many already working with psilocybin, but we’re interested in the potential biological activity of some of the other compounds in these mushrooms and whether they have any therapeutic value alone or in combination with psilocybin,” Perreault said.
Perreault’s experience has previously involved studies of the molecular and cellular mechanisms associated with medical conditions like depression or autism spectrum disorders. Her plan is to examine the signaling pathways that psilocybin might affect. “If there is any potential therapeutic value in these compounds, we would then bring them into some of the models I work with, such as those used to study specific aspects of depression or autism, to examine their therapeutic effects,” Perreault said.
In conclusion, Jones said that he believes increased access to mushrooms will allow more studies to be conducted. “There is a real need for a public supply of these mushrooms,” Jones said. We aim to create a supply of mushrooms to be used for preclinical and perhaps clinical trials in which the genetics and cultivation methodologies will be fully disclosed to researchers and the public.”
The press release also notes that the researchers plan to develop a synthetic mushroom growing method to make it easily reproduced. Typically, mushrooms are grown on grains or manure.
Psilocybin mushrooms are continuing to grow with interest among the medical community. Earlier this year in January, one organization presented evidence of mushroom’s therapeutic qualities and announced its intention to have the substance rescheduled in the United Nations 1971 UN Convention on Psychotropic Substances Act. In August, a study published in the journal JAMA Psychiatry showed how psilocybin has the potential to treat alcohol addiction. In mid-September, the University of Copenhagen began examining the effects of psilocybin to treat obesity. Just last week, Johns Hopkins University announced a study to analyze how psilocybin can help patients quit smoking. The substance has even become the muse for numerous high-profile musicians, such as Björk, Ellie Goulding, Kid Cudi, and Lil Nas X.
The state of Oregon is planning on finalizing its rules to regulate psilocybin by December 2022, while a few other states are presenting psilocybin allowances on the November ballot.
News
Study: Dispensaries Cut Down Heavy Drinking
As cannabis legalization expands across the United States, conversations continue to evolve about how increased access affects public health. A growing body of research now suggests that cannabis dispensaries may have a broader impact on community behavior than previously understood. Beyond simply providing regulated access to cannabis products, these retailers may influence patterns of alcohol use, particularly among adults who live nearby. Recent findings shed light on how shifts in cannabis policy can influence drinking habits and potentially contribute to healthier lifestyle outcomes.
Adults who reside in close proximity to licensed cannabis dispensaries are less likely to engage in binge drinking, according to data published in the American Journal of Preventive Medicine.
Oregon State University researchers assessed the relationship between local retail cannabis access and adults’ use of marijuana and alcohol over eight years.
They reported that proximity to cannabis retailers was associated with increased cannabis use by adults, but not by minors. They also reported that cannabis access was inversely associated with heavy alcohol use by young adults (those ages 21 to 24 years old) and seniors (those ages 65 and older).
“Consistent with substitution, … older adults and young adults showed access-related decreases in binge drinking,” the study’s authors reported.
They added: “Frequent or high-volume alcohol use causes myriad acute and lifelong health risks to drinkers and those around them. Therefore, a relative reduction in older and young adults’ high-risk drinking may be a net positive effect of shifting cannabis policies.”
The study’s conclusions are consistent with data published earlier this year, finding that many adults reduce their alcohol intake following the opening of state-licensed marijuana dispensaries.
These findings contribute to an increasingly nuanced picture of how cannabis dispensaries function within communities. Rather than promoting increased substance misuse, the presence of licensed cannabis retailers may encourage some adults to substitute cannabis for alcohol a shift that could potentially reduce the health risks associated with heavy drinking. While cannabis is not without its own considerations, regulated access may provide adults with an alternative that poses fewer long-term harms compared with chronic alcohol use.
As more states adopt regulated cannabis frameworks, researchers will continue exploring how these changes affect public health, safety, and substance use trends. For now, evidence suggests that cannabis dispensaries may play a surprising role in reducing harmful alcohol consumption among local adult populations. This research offers valuable insight for policymakers, health professionals, and communities navigating the evolving landscape of cannabis legalization.
Business
A Tipping Point for Cannabis: President Trump Champions CBD & Cannabis Science on Truth Social
When the President of the United States shares a video about the life changing potential of hemp derived CBD on his personal social media platform, it is more than news, it is a cultural shift.
For decades our government lied to us about cannabis. It demonized the plant, waged war on its users, and filled prisons while allowing pharmaceutical companies to flood the nation with addictive and deadly drugs. For over a century we have been fighting uphill, not just for legalization, but for truth, for science, and for the right to heal ourselves naturally.
Now in 2025, the most powerful political figure on Earth is using his own voice and platform to talk about the endocannabinoid system and the science backed benefits of CBD. That is monumental. It is validation for everyone who has fought, been arrested, been silenced, and been dismissed for telling this truth. The President’s video post is already being described as a pivotal moment in cannabis history, and President Trump CBD Cannabis Science Truth Social is trending across platforms as advocates celebrate the breakthrough.
The Science Behind the Endocannabinoid System
The video begins by introducing something most people, including many doctors, still know little about, the endocannabinoid system. Discovered in the 1990s, the ECS is a network of receptors and signaling molecules that works as the body’s master regulator, coordinating communication between major systems like the nervous, immune, cardiovascular, and digestive systems.
The roots of this discovery go back much further. CBD was first isolated in 1940 by American chemist Roger Adams, but it was Dr. Raphael Mechoulam, an Israeli organic chemist, who fully elucidated the chemical structure of CBD and identified its stereochemistry in the 1960s. His pioneering work not only opened the door to modern cannabinoid science but also earned him the title “Godfather of Cannabis Research.” It was this foundation that led to the identification of the endocannabinoid system itself decades later, revealing how cannabinoids interact with our physiology on a fundamental level.
The ECS is now widely recognized as a vital part of human biology, with extensive research supported by the National Institutes of Health. When functioning properly, the ECS acts like the conductor of an orchestra, ensuring every section plays in harmony. As we age, the system weakens. That imbalance is linked to inflammation, chronic pain, cognitive decline, sleep problems, and many other conditions associated with aging.
Mainstream medicine often addresses these issues with pharmaceutical band aids, dangerous and addictive drugs that treat symptoms rather than root causes. Lifestyle changes such as diet and exercise help, but they only partially support the ECS and do so slowly over time.
Hemp Derived CBD: A Game Changer for Aging
Here is where the science gets exciting. As the video explains, the ECS can be restored much more quickly with hemp derived CBD. Strengthening this system naturally helps the body regain balance, reducing pain, improving sleep, lowering stress, slowing disease progression, and even extending healthy lifespan.
It is not theoretical. One in five seniors is already using CBD to manage pain, arthritis, cancer symptoms, sleep disorders, Alzheimer’s, and more. Despite decades of research and acknowledgment from institutions like the National Institutes of Health, most physicians receive no training on the ECS. There are still no FDA standards for CBD products on the market. If that were the case for any other class of medicine, it would be considered malpractice.
The World Health Organization has confirmed CBD’s excellent safety profile and non addictive nature in its critical review report. The result is that millions of older Americans are suffering unnecessarily when a safe and natural solution exists.
Hemp derived CBD is a powerful first step in restoring balance to the endocannabinoid system, but it is only part of the picture. Research shows that full spectrum cannabis extracts, which include a broader range of cannabinoids and terpenes, can work even more effectively. Complete concentrated cannabis oil, containing the full spectrum of natural endocannabinoids, may deliver the most profound results for certain patients. Expanding access to these therapies will be essential if we want to unlock the full healing potential of this plant.
The Economic and Social Impact
The video cites a powerful figure. A PricewaterhouseCoopers analysis estimates that fully integrating cannabis into the healthcare system could save the United States nearly 64 billion dollars annually. These savings reflect reduced pharmaceutical dependency, fewer hospitalizations, improved chronic disease outcomes, and enhanced quality of life for aging Americans. You can read more about PwC’s research on healthcare innovation here.
It is a financial argument, but it is also a moral one. Why should our elders endure pain, anxiety, and cognitive decline when nature has given us tools to help them live longer, happier, and healthier lives?
A Call to Action: Finish What the Farm Bill Started
The message concludes by crediting the 2018 Farm Bill, championed by President Trump, for legalizing hemp and laying the groundwork for today’s CBD market. The Farm Bill was just the first step.
Now the call is for bold next moves.
- Educate doctors about the endocannabinoid system
- Include CBD under Medicare coverage
- Provide clear federal standards for CBD quality and dosing
These steps would constitute the most significant senior health reform in modern history, one that would transform aging and cement a powerful legacy for any administration that makes it happen.
What This Means for Future Cannabis Medicine
For those of us who have been in the cannabis community for decades, this is not just another news story. It is a signal that our movement is winning. A conversation that was once criminalized and censored is now being amplified by the President of the United States on his own platform.
It means the science is undeniable. It means the truth can no longer be buried. It means the wall of prohibition is cracking, not just legally, but culturally, scientifically, and politically.
It also means that everything we have been fighting for at 420 Magazine since 1993, education, access, healing, and justice, is finally moving full steam ahead. The President Trump CBD Cannabis Science Truth Social moment is proof that science and policy are finally converging.
Business
New Mexico cannabis operator fined, loses license for alleged BioTrack fraud
New Mexico regulators fined a cannabis operator nearly $300,000 and revoked its license after the company allegedly created fake reports in the state’s traceability software.
The New Mexico Cannabis Control Division (CCD) accused marijuana manufacturer and retailer Golden Roots of 11 violations, according to Albuquerque Business First.
Golden Roots operates the The Cannabis Revolution Dispensary.
The majority of the violations are related to the Albuquerque company’s improper use of BioTrack, which has been New Mexico’s track-and-trace vendor since 2015.
The CCD alleges Golden Roots reported marijuana production only two months after it had received its vertically integrated license, according to Albuquerque Business First.
Because cannabis takes longer than two months to be cultivated, the CCD was suspicious of the report.
After inspecting the company’s premises, the CCD alleged Golden Roots reported cultivation, transportation and sales in BioTrack but wasn’t able to provide officers who inspected the site evidence that the operator was cultivating cannabis.
In April, the CCD revoked Golden Roots’ license and issued a $10,000 fine, according to the news outlet.
The company requested a hearing, which the regulator scheduled for Sept. 1.
At the hearing, the CCD testified that the company’s dried-cannabis weights in BioTrack were suspicious because they didn’t seem to accurately reflect how much weight marijuana loses as it dries.
Company employees also poorly accounted for why they were making adjustments in the system of up to 24 pounds of cannabis, making comments such as “bad” or “mistake” in the software, Albuquerque Business First reported.
Golden Roots was fined $298,972.05 – the amount regulators allege the company made selling products that weren’t properly accounted for in BioTrack.
The CCD has been cracking down on cannabis operators accused of selling products procured from out-of-state or not grown legally:
- Regulators alleged in August that Albuquerque dispensary Sawmill Sweet Leaf sold out-of-state products and didn’t have a license for extraction.
- Paradise Exotics Distro lost its license in July after regulators alleged the company sold products made in California.
Golden Roots was the first alleged rulebreaker in New Mexico to be asked to pay a large fine.
Source: https://mjbizdaily.com/new-mexico-cannabis-operator-fined-loses-license-for-alleged-biotrack-fraud/
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