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Data Suggests The Perfect CBD To THC Ratio

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When the two are combined in varying ratios, they enhance each other’s beneficial properties synergistically. Here’s what researchers believe to be the best ratio for therapeutic effects.

Researchers from the University of Colorado’s Anschutz Medical Campus analyzed the impact of cannabis flowers with almost equal ratios of THC and CBD, and its effects on subjects. The data suggests the perfect CBD to THC ratio

The study, published in the journal Addiction Biology, examined subjects who were tasked to smoke cannabis flower with various ratios, which were randomly assigned. These included 24% THC and 1% CBD, 23% CBD and 1% THC, as well as flowers that had almost equal ratios of each, 10% THC and 9% CBD. After an hour, the researchers measured their effects.

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They found that the patients who smoked the THC dominant cannabis and those who smoked nearly equal ratios and those who smoked the flowers with almost equal ratios experienced similar positive benefits. The difference was that the participants who consumed samples with nearly equal ratios reported less negative side effects including paranoia and anxiety.

“This is one of the first studies to examine the differential effects of various THC and CBD ratios using cannabis flower chemovars that are widely available in state-regulated markets. The present findings suggest that CBD may be associated with an overall reduction of THC exposure and may mitigate the negative psychotomimetic effects of THC without diminishing the effects of THC that individuals report liking,” they write.

“The results of the present study suggest that participants using the THC+CBD chemovar had significantly lower plasma THC levels and reported less paranoia and anxiety as compared to participants using the THC dominant chemovar. Importantly, despite these differences, participants in both the THC+CBD and THC conditions reported similar positive subjective effects… The harm reduction implication of these findings is that cannabis chemovars containing CBD may result in less overall exposure to THC and subsequently less potential for harm, particularly with respect to the psychotomimetic effects of THC,” they concluded.

Why Ratio Matters

CBD and THC are the two primary cannabinoids in the cannabis plant. They each have their own properties; THC is the psychoactive compound that is responsible for making you feel high. The more THC a flower or product contains, the higher you will feel. But aside from just getting you high, THC is widely used for its medicinal properties such as its ability to induce appetite, treat insomnia, stop nausea, and provide relief from pain. However, the right dose is essential because too much THC can make people feel paranoid and anxious. On the other hand, CBD is non-psychoactive and is used for relaxation, insomnia, anxiety, pain, and much more.

When the two are combined in varying ratios, they enhance each other’s beneficial properties synergistically in what is known as the “entourage effect”. Aside from that, all of us have a different biological makeup which is why how you react to CBD may be different from how your friend reacts to CBD, even if you both took exactly the same dose.

It has been recognized by scientists that the ideal dose for most people who want to achieve the most therapeutic benefits is an equal ratio of each, or 1:1 THC CBD. This ratio can help you stay productive without feeling too high since CBD counteracts the highs of THC, while also offering a wide range of health benefits including pain management, anxiety reduction, and better sleep among others.

Common Ratios

When shopping around for cannabis products, those that use a combination of both cannabinoids present various ratios. Here are the most common ratios:

0:1 CBD THC: With no CBD in the product, you will be able to feel the highs of THC which many find to be uplifting and euphoric, while reducing stress. If you are one of those people who are sensitive to THC or have a low tolerance, you may be prone to anxiety and paranoia. However, many people prefer it because it provides relief from pain and inflammation while improving energy and mood.

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1:0 CBD THC: A product that has no THC will not make you feel any kind of high. People who enjoy the relaxation brought about by CBD will appreciate these types of products as they can mildly sedate while still improving your mood and helping to reduce anxiety and panic attacks.

1:1 CBD THC: For people who aren’t familiar with CBD and THC, this is the recommended ratio to start with. You will be able to experience the best of both worlds, but also the presence of CBD will negate getting too high from the THC. In addition, you will be able to stay functional and productive.

1:9 or more: These are usually high-THC products, which means that you will likely experience the characteristics that are typically associated with THC. These may be beneficial for people who are suffering from severe pain, nausea, migraines, lack of appetite due to chemotherapy or radiation, and more. Just keep in mind that it also means you will get a high.

Aside from these, you will also encounter other ratios in the market such as 2:1, 3:1, or 4:1 as well as 25: 1 and others. If you aren’t sure where to start, remember that the more CBD it contains, the less THC psychoactivity you will experience. If you don’t want to get high, always opt for a product that has a higher CBD content or an equal ratio.

Talk to a budtender at your nearest dispensary to learn more about recommendations based on your personal needs. These ratios are available in many cannabis products from oils to tinctures, edibles, and so much more.

Source: https://thefreshtoast.com/cannabis/the-perfect-cbd-to-thc-ratio-this-is-what-a-new-study-suggests/

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New Mexico cannabis operator fined, loses license for alleged BioTrack fraud

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New Mexico regulators fined a cannabis operator nearly $300,000 and revoked its license after the company allegedly created fake reports in the state’s traceability software.

The New Mexico Cannabis Control Division (CCD) accused marijuana manufacturer and retailer Golden Roots of 11 violations, according to Albuquerque Business First.

Golden Roots operates the The Cannabis Revolution Dispensary.

The majority of the violations are related to the Albuquerque company’s improper use of BioTrack, which has been New Mexico’s track-and-trace vendor since 2015.

The CCD alleges Golden Roots reported marijuana production only two months after it had received its vertically integrated license, according to Albuquerque Business First.

Because cannabis takes longer than two months to be cultivated, the CCD was suspicious of the report.

After inspecting the company’s premises, the CCD alleged Golden Roots reported cultivation, transportation and sales in BioTrack but wasn’t able to provide officers who inspected the site evidence that the operator was cultivating cannabis.

In April, the CCD revoked Golden Roots’ license and issued a $10,000 fine, according to the news outlet.

The company requested a hearing, which the regulator scheduled for Sept. 1.

At the hearing, the CCD testified that the company’s dried-cannabis weights in BioTrack were suspicious because they didn’t seem to accurately reflect how much weight marijuana loses as it dries.

Company employees also poorly accounted for why they were making adjustments in the system of up to 24 pounds of cannabis, making comments such as “bad” or “mistake” in the software, Albuquerque Business First reported.

Golden Roots was fined $298,972.05 – the amount regulators allege the company made selling products that weren’t properly accounted for in BioTrack.

The CCD has been cracking down on cannabis operators accused of selling products procured from out-of-state or not grown legally:

Golden Roots was the first alleged rulebreaker in New Mexico to be asked to pay a large fine.

Source: https://mjbizdaily.com/new-mexico-cannabis-operator-fined-loses-license-for-alleged-biotrack-fraud/

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Marijuana companies suing US attorney general in federal prohibition challenge

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Four marijuana companies, including a multistate operator, have filed a lawsuit against U.S. Attorney General Merrick Garland in which they allege the federal MJ prohibition under the Controlled Substances Act is no longer constitutional.

According to the complaint, filed Thursday in U.S. District Court in Massachusetts, retailer Canna Provisions, Treevit delivery service CEO Gyasi Sellers, cultivator Wiseacre Farm and MSO Verano Holdings Corp. are all harmed by “the federal government’s unconstitutional ban on cultivating, manufacturing, distributing, or possessing intrastate marijuana.”

Verano is headquartered in Chicago but has operations in Massachusetts; the other three operators are based in Massachusetts.

The lawsuit seeks a ruling that the “Controlled Substances Act is unconstitutional as applied to the intrastate cultivation, manufacture, possession, and distribution of marijuana pursuant to state law.”

The companies want the case to go before the U.S. Supreme Court.

They hired prominent law firm Boies Schiller Flexner to represent them.

The New York-based firm’s principal is David Boies, whose former clients include Microsoft, former presidential candidate Al Gore and Elizabeth Holmes’ disgraced startup Theranos.

Similar challenges to the federal Controlled Substances Act (CSA) have failed.

One such challenge led to a landmark Supreme Court decision in 2005.

In Gonzalez vs. Raich, the highest court in the United States ruled in a 6-3 decision that the commerce clause of the U.S. Constitution gave Congress the power to outlaw marijuana federally, even though state laws allow the cultivation and sale of cannabis.

In the 18 years since that ruling, 23 states and the District of Columbia have legalized adult-use marijuana and the federal government has allowed a multibillion-dollar cannabis industry to thrive.

Since both Congress and the U.S. Department of Justice, currently headed by Garland, have declined to intervene in state-licensed marijuana markets, the key facts that led to the Supreme Court’s 2005 ruling “no longer apply,” Boies said in a statement Thursday.

“The Supreme Court has since made clear that the federal government lacks the authority to regulate purely intrastate commerce,” Boies said.

“Moreover, the facts on which those precedents are based are no longer true.”

Verano President Darren Weiss said in a statement the company is “prepared to bring this case all the way to the Supreme Court in order to align federal law with how Congress has acted for years.”

While the Biden administration’s push to reschedule marijuana would help solve marijuana operators’ federal tax woes, neither rescheduling nor modest Congressional reforms such as the SAFER Banking Act “solve the fundamental issue,” Weiss added.

“The application of the CSA to lawful state-run cannabis business is an unconstitutional overreach on state sovereignty that has led to decades of harm, failed businesses, lost jobs, and unsafe working conditions.”

Source: https://mjbizdaily.com/marijuana-companies-suing-us-attorney-general-to-overturn-federal-prohibition/

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Alabama to make another attempt Dec. 1 to award medical cannabis licenses

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Alabama regulators are targeting Dec. 1 to award the first batch of medical cannabis business licenses after the agency’s first two attempts were scrapped because of scoring errors and litigation.

The first licenses will be awarded to individual cultivators, delivery providers, processors, dispensaries and state testing labs, according to the Alabama Medical Cannabis Commission (AMCC).

Then, on Dec. 12, the AMCC will award licenses for vertically integrated operations, a designation set primarily for multistate operators.

Licenses are expected to be handed out 28 days after they have been awarded, so MMJ production could begin in early January, according to the Alabama Daily News.

That means MMJ products could be available for patients around early March, an AMCC spokesperson told the media outlet.

Regulators initially awarded 21 business licenses in June, only to void them after applicants alleged inconsistencies with how the applications were scored.

Then, in August, the state awarded 24 different licenses – 19 went to June recipients – only to reverse themselves again and scratch those licenses after spurned applicants filed lawsuits.

A state judge dismissed a lawsuit filed by Chicago-based MSO Verano Holdings Corp., but another lawsuit is pending.

Source: https://mjbizdaily.com/alabama-plans-to-award-medical-cannabis-licenses-dec-1/

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