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Canadian University Granted License To Study Psilocybin Mushrooms

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Researchers at the University of Guelph (UG) in Ontario, Canada recently received approval to study psilocybin mushrooms.

Dr. Max Jones and Dr. Gale Bozzo, two professors at UG’s Ontario Agricultural College (Department of Plant Agriculture), received a Health Canada “dealer’s license” on Oct. 25. The license permits the cultivation of psilocybin mushrooms, and is one of the first universities in Canada to be permitted to do so.

“We are very excited about this approval as it will allow us to study these psychedelic mushrooms to better understand their biology and genetics, examine what other functional compounds they might contain, and provide well-characterized and chemically consistent material for preclinical and potentially clinical evaluation,” Jones said. He previously received a license to study cannabis back in November 2018 as well. 

According to Jones, there are more than 200 species of mushrooms that can produce psilocybin. “Those species aren’t that closely related; they’re diverse,” Jones said in a press release. “So that makes scientists like me wonder: what else are these mushrooms producing? If you have 200 species producing a compound that affects the human brain, it’s likely they are producing other interesting compounds, too.”

Psilocybin therapy has become a popular treatment for conditions such as depression, addiction, obsessive-compulsive disorder, and post-traumatic stress disorder. According to Dr. Melissa Perreault, Professor in Ontario Veterinary College’s Department of Biomedical Sciences and another researchers involved with the study, there’s a specific function that they’re hoping to examine. “There are many already working with psilocybin, but we’re interested in the potential biological activity of some of the other compounds in these mushrooms and whether they have any therapeutic value alone or in combination with psilocybin,” Perreault said.

Perreault’s experience has previously involved studies of the molecular and cellular mechanisms associated with medical conditions like depression or autism spectrum disorders. Her plan is to examine the signaling pathways that psilocybin might affect. “If there is any potential therapeutic value in these compounds, we would then bring them into some of the models I work with, such as those used to study specific aspects of depression or autism, to examine their therapeutic effects,” Perreault said.

In conclusion, Jones said that he believes increased access to mushrooms will allow more studies to be conducted. “There is a real need for a public supply of these mushrooms,” Jones said. We aim to create a supply of mushrooms to be used for preclinical and perhaps clinical trials in which the genetics and cultivation methodologies will be fully disclosed to researchers and the public.”

The press release also notes that the researchers plan to develop a synthetic mushroom growing method to make it easily reproduced. Typically, mushrooms are grown on grains or manure.

Psilocybin mushrooms are continuing to grow with interest among the medical community. Earlier this year in January, one organization presented evidence of mushroom’s therapeutic qualities and announced its intention to have the substance rescheduled in the United Nations 1971 UN Convention on Psychotropic Substances Act. In August, a study published in the journal JAMA Psychiatry showed how psilocybin has the potential to treat alcohol addiction. In mid-September, the University of Copenhagen began examining the effects of psilocybin to treat obesity. Just last week, Johns Hopkins University announced a study to analyze how psilocybin can help patients quit smoking. The substance has even become the muse for numerous high-profile musicians, such as Björk, Ellie Goulding, Kid Cudi, and Lil Nas X.

The state of Oregon is planning on finalizing its rules to regulate psilocybin by December 2022, while a few other states are presenting psilocybin allowances on the November ballot.

Source: https://hightimes.com/psychedelics/canadian-university-granted-license-to-study-psilocybin-mushrooms/

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New Mexico cannabis operator fined, loses license for alleged BioTrack fraud

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New Mexico regulators fined a cannabis operator nearly $300,000 and revoked its license after the company allegedly created fake reports in the state’s traceability software.

The New Mexico Cannabis Control Division (CCD) accused marijuana manufacturer and retailer Golden Roots of 11 violations, according to Albuquerque Business First.

Golden Roots operates the The Cannabis Revolution Dispensary.

The majority of the violations are related to the Albuquerque company’s improper use of BioTrack, which has been New Mexico’s track-and-trace vendor since 2015.

The CCD alleges Golden Roots reported marijuana production only two months after it had received its vertically integrated license, according to Albuquerque Business First.

Because cannabis takes longer than two months to be cultivated, the CCD was suspicious of the report.

After inspecting the company’s premises, the CCD alleged Golden Roots reported cultivation, transportation and sales in BioTrack but wasn’t able to provide officers who inspected the site evidence that the operator was cultivating cannabis.

In April, the CCD revoked Golden Roots’ license and issued a $10,000 fine, according to the news outlet.

The company requested a hearing, which the regulator scheduled for Sept. 1.

At the hearing, the CCD testified that the company’s dried-cannabis weights in BioTrack were suspicious because they didn’t seem to accurately reflect how much weight marijuana loses as it dries.

Company employees also poorly accounted for why they were making adjustments in the system of up to 24 pounds of cannabis, making comments such as “bad” or “mistake” in the software, Albuquerque Business First reported.

Golden Roots was fined $298,972.05 – the amount regulators allege the company made selling products that weren’t properly accounted for in BioTrack.

The CCD has been cracking down on cannabis operators accused of selling products procured from out-of-state or not grown legally:

Golden Roots was the first alleged rulebreaker in New Mexico to be asked to pay a large fine.

Source: https://mjbizdaily.com/new-mexico-cannabis-operator-fined-loses-license-for-alleged-biotrack-fraud/

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Marijuana companies suing US attorney general in federal prohibition challenge

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Four marijuana companies, including a multistate operator, have filed a lawsuit against U.S. Attorney General Merrick Garland in which they allege the federal MJ prohibition under the Controlled Substances Act is no longer constitutional.

According to the complaint, filed Thursday in U.S. District Court in Massachusetts, retailer Canna Provisions, Treevit delivery service CEO Gyasi Sellers, cultivator Wiseacre Farm and MSO Verano Holdings Corp. are all harmed by “the federal government’s unconstitutional ban on cultivating, manufacturing, distributing, or possessing intrastate marijuana.”

Verano is headquartered in Chicago but has operations in Massachusetts; the other three operators are based in Massachusetts.

The lawsuit seeks a ruling that the “Controlled Substances Act is unconstitutional as applied to the intrastate cultivation, manufacture, possession, and distribution of marijuana pursuant to state law.”

The companies want the case to go before the U.S. Supreme Court.

They hired prominent law firm Boies Schiller Flexner to represent them.

The New York-based firm’s principal is David Boies, whose former clients include Microsoft, former presidential candidate Al Gore and Elizabeth Holmes’ disgraced startup Theranos.

Similar challenges to the federal Controlled Substances Act (CSA) have failed.

One such challenge led to a landmark Supreme Court decision in 2005.

In Gonzalez vs. Raich, the highest court in the United States ruled in a 6-3 decision that the commerce clause of the U.S. Constitution gave Congress the power to outlaw marijuana federally, even though state laws allow the cultivation and sale of cannabis.

In the 18 years since that ruling, 23 states and the District of Columbia have legalized adult-use marijuana and the federal government has allowed a multibillion-dollar cannabis industry to thrive.

Since both Congress and the U.S. Department of Justice, currently headed by Garland, have declined to intervene in state-licensed marijuana markets, the key facts that led to the Supreme Court’s 2005 ruling “no longer apply,” Boies said in a statement Thursday.

“The Supreme Court has since made clear that the federal government lacks the authority to regulate purely intrastate commerce,” Boies said.

“Moreover, the facts on which those precedents are based are no longer true.”

Verano President Darren Weiss said in a statement the company is “prepared to bring this case all the way to the Supreme Court in order to align federal law with how Congress has acted for years.”

While the Biden administration’s push to reschedule marijuana would help solve marijuana operators’ federal tax woes, neither rescheduling nor modest Congressional reforms such as the SAFER Banking Act “solve the fundamental issue,” Weiss added.

“The application of the CSA to lawful state-run cannabis business is an unconstitutional overreach on state sovereignty that has led to decades of harm, failed businesses, lost jobs, and unsafe working conditions.”

Source: https://mjbizdaily.com/marijuana-companies-suing-us-attorney-general-to-overturn-federal-prohibition/

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Alabama to make another attempt Dec. 1 to award medical cannabis licenses

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Alabama regulators are targeting Dec. 1 to award the first batch of medical cannabis business licenses after the agency’s first two attempts were scrapped because of scoring errors and litigation.

The first licenses will be awarded to individual cultivators, delivery providers, processors, dispensaries and state testing labs, according to the Alabama Medical Cannabis Commission (AMCC).

Then, on Dec. 12, the AMCC will award licenses for vertically integrated operations, a designation set primarily for multistate operators.

Licenses are expected to be handed out 28 days after they have been awarded, so MMJ production could begin in early January, according to the Alabama Daily News.

That means MMJ products could be available for patients around early March, an AMCC spokesperson told the media outlet.

Regulators initially awarded 21 business licenses in June, only to void them after applicants alleged inconsistencies with how the applications were scored.

Then, in August, the state awarded 24 different licenses – 19 went to June recipients – only to reverse themselves again and scratch those licenses after spurned applicants filed lawsuits.

A state judge dismissed a lawsuit filed by Chicago-based MSO Verano Holdings Corp., but another lawsuit is pending.

Source: https://mjbizdaily.com/alabama-plans-to-award-medical-cannabis-licenses-dec-1/

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